Update on thyroid tumors with DICER1 mutation
10.13315/j.cnki.cjcep.2025.01.003
- VernacularTitle:DICER1基因突变甲状腺肿瘤研究进展
- Author:
Juan TANG
1
;
Zhiyan LIU
1
Author Information
1. 上海交通大学医学院附属第六人民医院病理科,上海 200233
- Publication Type:Journal Article
- Keywords:
thyroid neoplasm;
follicular thyroid tumour;
thyroid nodular disease;
DICER1 syndrome;
DICER1 mutation
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(1):9-13
- CountryChina
- Language:Chinese
-
Abstract:
With the further comprehensive understanding of pathologists in the morphological characteristics of DICER1-related thyroid tumors,and the widespread application of multi-gene detection technology,the detection rate of these tumors is gradually increasing.DICER1 mutations can be detected in benign,low-risk,and malignant thyroid tumors.It is particularly noteworthy that tumors with germline mutations and in pediatric patients often exhibit more ag-gressive and prone to recurrent.Therefore,it is important to identify and diagnose these lesions.This article summarize the advancements in DICER1 mutation-related thyroid tumors through systematic interpretation.
