Allergen Sensitization of 2610 Children in Qianwan New District of Ningbo City
10.13241/j.cnki.pmb.2025.14.005
- VernacularTitle:宁波市前湾新区2610例过敏性疾病患儿过敏原特异性IgE分布特征研究
- Author:
Xue-nai CHEN
1
;
Jian-jun XIAO
;
Ling-ya LU
;
Qi ZHAO
;
Yan-ming LU
Author Information
1. 上海交通大学医学院附属仁济医院儿科 上海 201112
- Publication Type:Journal Article
- Keywords:
Allergen specific IgE;
Sensitization;
Allergic diseases;
Children;
Qianwan New District of Ningbo City
- From:
Progress in Modern Biomedicine
2025;25(14):2279-2287
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate distribution characteristics of allergen specific IgE of children with allergic diseases in Qianwan New District of Ningbo City,and provide guidance for clinical prophylaxis,cure and management of allergic diseases.Methods:This retrospective study enrolled pediatric patients with suspected allergic diseases presenting to the Department of Pediatrics at Ningbo Hangzhou Bay Hospital between January 2019 and October 2023.Allergen specific IgE and total IgE were detected by microarray enzyme-linked immunoassay.Results:52.9％of the investigated children are allergic to at least one allergen,39.8％had multiple sensitization.The main inhalation allergens were Dermatophagoides pteronyssinus(32.8％),D.farinae(32.3％),Blomia tropicalis(7.7％),Bermuda Grass(6.6％)and Timothy Grass(6.0％).The main food allergens were Egg White(23.1％),Milk(11.7％),Almond(4.9％)and Peanut(4.3％).Compared with girls(50.1％),boys(54.7％)are more likely to be sensitized to allergens.Infants and young children are predominantly affected by inhalation allergen;however,after three years old,there is a notable shift in the sensitization pattern,with inhalation allergens gradually becoming the predominant type of sensitization.Conclusions:It is common for children in Qianwan New District of Ningbo city to be sensitized to inhalation and food allergens.In addition to Mite,Egg White and Milk,Bermuda Grass and Timothy Grass are also important allergens.The distribution of allergens varies according to genders,age,and year.
