Research progress on the role of dendritic cells in the immunity of head and neck squamous cell carcinoma
10.13315/j.cnki.cjcep.2025.01.013
- VernacularTitle:树突状细胞在头颈部鳞状细胞癌免疫作用研究进展
- Author:
Jiaxin NIU
1
;
Ju ZENG
;
Cong ZHANG
;
Xinxin YANG
;
Hongxue MENG
Author Information
1. 哈尔滨医科大学附属肿瘤医院病理科,哈尔滨 150081
- Publication Type:Journal Article
- Keywords:
head and neck squamous cell carcinoma;
dendritic cell;
mechanism of action;
literature review
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(1):81-85,92
- CountryChina
- Language:Chinese
-
Abstract:
Head and neck squamous cell carcinoma(HNSCC)is the sixth most common malignant tumor in the world.Due to its high incidence,poor prognosis,relapse-prone characteristics,and the existence of treatment resist-ance,HNSCC has a serious impact on patients'daily lives.As a bridge between innate immunity and adaptive immu-nity,dendritic cell(DC)plays a crucial role in tumor progression.In recent years,numerous studies have found that DC has complex and diverse functions in the tumor microenvironment(TME),and has a significant impact on the oc-currence and development of HNSCC.In this article,we provide a review of the mechanism of DC in HNSCC TME.
