Analysis of the Symptom Improvement Effect of Self-made Eczema and Dermatitis Conditioning Formula Combined with Qingpeng Ointment on Damp Heat Intrinsic Eczema
10.13241/j.cnki.pmb.2025.13.008
- VernacularTitle:自拟湿疹皮炎调理方联合青鹏膏剂对湿热内蕴型湿疹的症状改善作用分析
- Author:
Lei QUE
1
;
Hong-qiao SHI
1
;
Jian QI
1
;
Yue-hong LI
1
;
Li ZHOU
1
Author Information
1. 南京中医药大学附属南京中医院/南京市中医院皮肤科 江苏南京 210001
- Publication Type:Journal Article
- Keywords:
Eczema and dermatitis conditioning formula;
Qingpeng ointment;
Damp heat internal type;
Eczema
- From:
Progress in Modern Biomedicine
2025;25(13):2154-2159
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the symptom improvement effect of a self-made eczema and dermatitis conditioning formula combined with Qingpeng ointment on damp heat type eczema.Methods:A prospective study was conducted on 70 patients with damp heat type eczema ffrom June 2023 to August 2024.Random number table method was used to divide them into two groups.Among them,35 cases were in the single group and treated with Qingpeng plaster alone,while the remaining 35 cases were in the combination group and treated with a self-made eczema and dermatitis conditioning formula orally combined with Qingpeng plaster.After one month of treatment,the clinical efficacy,TCM syndrome scores before and Post-treatment,disappearance time of main symptoms,and the long-term recurrence rate was also compared.Results:The total effective rate of the combined group was 91.43%,which was higher than that of the single group(71.43%,P<0.05);Before treatment,there was no significant difference in the scores of TCM syndromes between the two groups(P>0.05).Post-treatment,the scores of TCM syndromes related to the main symptoms(skin erythema,papules,blisters,obvious exudation,severe itching,and burning sensation in the skin lesions)and secondary symptoms(dry mouth,bitter mouth,yellow and red urine,sticky stool or constipation)in both groups decreased,and the combined group was lower than the single group(P<0.05);The disappearance time of skin burning sensation,exudation,erythema,itching,and skin lesion related symptoms in the combined group was shorter than that in the single group(P<0.05);Two groups of patients were followed up for six months Post-treatment,and there were no lost cases during the follow-up period.There was no difference between the combined group and the single group(x2=3.214,P=0.073).Conclusion:The combination of self-made eczema and dermatitis conditioning formula and Qingpeng ointment can improve the clinical efficacy of damp heat type eczema,reduce its TCM syndrome score,shorten the duration of main symptoms,and lower the long-term recurrence rate of patients.The mechanism may be related to the regulation of T lymphocyte subsets in eczema patients by the self-made eczema and dermatitis conditioning formula,and the reduction of the body's inflammatory response.