Research progress in energy metabolism and diseases during reproduction
10.3760/cma.j.cn101441-20221009-00438
- VernacularTitle:生殖过程中能量代谢调控与疾病的研究进展
- Author:
Chen DU
1
;
Debang LI
1
;
Qian ZHANG
1
;
Xiujuan CHEN
1
Author Information
1. 内蒙古医科大学附属医院生殖医学中心，呼和浩特 010050
- Publication Type:Journal Article
- Keywords:
Reproduction;
Energy metabolism;
Glycolysis;
Lipid metabolism;
Protein metabolism
- From:
Chinese Journal of Reproduction and Contraception
2023;43(10):1073-1078
- CountryChina
- Language:Chinese
-
Abstract:
Metabolism is an important physiological activity throughout the cell life cycle, and energy substrates play an important role in regulating follicle development, maintaining sperm motility, influencing preimplantation embryo development and inducing immune tolerance at the maternal-fetal interface. Normal metabolism can promote cell growth and development, while abnormal metabolism can lead to dysfunction, and is closely related to the occurrence and development of diseases related to female reproduction. This study provides an overview of glucose metabolism, lipid metabolism and protein (amino acid) metabolism in the reproductive process and their relationship with several reproductive diseases. It is expected to optimize in vitro maturation of oocytes by regulating the energy metabolism, and provide new approaches for the study of energy metabolism at the maternal-fetal interface of embryo implantation and the diagnosis and treatment of infertility.
