Study on the relationship between vitamin D level and ovarian blood flow and ovarian reserve function
10.3760/cma.j.cn101441-20220518-00217
- VernacularTitle:血清维生素D水平与卵巢血流动力学及卵巢储备功能相关性研究
- Author:
Huimin SHEN
1
;
Pidong GONG
1
;
Chao WANG
1
;
Ruijing WANG
1
;
Yu LIU
1
;
Yaxin WANG
1
;
Yanhui ZHANG
1
;
Meimei LIU
1
Author Information
1. 哈尔滨医科大学附属第二医院妇产科，哈尔滨 150000
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Hemodynamics;
Ovarian reserve;
Anti-Müllerian hormone
- From:
Chinese Journal of Reproduction and Contraception
2023;43(8):799-805
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the correlation between serum vitamin D level and ovarian artery blood flow index and ovarian reserve function in women.Methods:A retrospective cohort study was conducted. Women aged from 18 to 40 years who were admitted to the Department of Obstetrics and Gynecology of the Second Affiliated Hospital of Harbin Medical University from September 2020 to November 2021 and had regular sexual life were selected as subjects. The data of age, height and weight were collected. And the indexes of vitamin D, anti-Müllerian hormone (AMH), luteinizing hormone and follicle-stimulating hormone were detected in the laboratory. Color Doppler ultrasound was used to measure antral follicle count and bilateral ovarian interstitial artery blood stream resistance index (RI) and plusatility index (PI) in early follicular phase. Multiple linear regression was used to analyze the related factors of serum vitamin D level.Results:A total of 218 women were included in the study, including 137 cases of vitamin D deficiency, accounting for 62.8%, 39 cases of vitamin D insufficiency, accounting for 17.9%, 42 cases of normal vitamin D, accounting for 19.3%. Multiple linear regression analysis showed that there was a negative correlation between serum vitamin D level and ovarian blood flow ( P=0.024), but no correlation with other indexes (all P>0.05). Conclusion:Serum vitamin D level affected ovarian interstitial artery blood flow RI to some extent, but had no significant correlation with ovarian interstitial artery blood flow PI, serum AMH level and other indexes related to ovarian reserve function.
