Research progress and application of single nucleotide polymorphism detection methods for genetic quality testing of laboratory animals
10.3969/j.issn.1005-4847.2024.12.010
- VernacularTitle:SNP检测方法在实验动物遗传质量检测中的研究进展和应用
- Author:
Yue ZHANG
1
;
Xiangru LI
;
Jinqiang QUAN
;
Caixia GAO
;
Changyou XIA
;
Shengguo ZHAO
Author Information
1. 甘肃农业大学动物科学技术学院,兰州 730070
- Publication Type:Journal Article
- Keywords:
laboratory animal;
genetic quality;
SNP;
detection method
- From:
Acta Laboratorium Animalis Scientia Sinica
2024;32(12):1588-1593
- CountryChina
- Language:Chinese
-
Abstract:
Laboratory animals provide an important experimental resource for life science research,and their uniformity plays a key role in the accuracy and reliability of the experimental result.Genetic quality testing of laboratory animals is thus essential to evaluate the genetic quality of laboratory animals.Progress in modern biotechnology has led to improvements in the method of genetic testing of experimental animals.Single nucleotide polymorphisms,as molecular markers,have been widely used in genetic testing of laboratory animals,and method for their detection in laboratory animals have been updated,in line with biotechnology advances.In this paper,we review current research progress and the application of SNP detection method for genetic quality testing of laboratory animals,and discuss the advantages and disadvantages of various detection method,with a view to providing a reference basis for genetic quality testing of laboratory animals.
