Brain edema after oocyte retrieval: a case report and literature review
10.3760/cma.j.cn101441-20211104-00486
- VernacularTitle:取卵术后脑水肿1例报道与文献回顾
- Author:
Lijuan FAN
1
;
Yilin JIANG
;
Wen WEN
;
Zhengli DI
;
Honghong SUN
;
Haixia DUAN
;
Yanrui CHEN
;
Sirui LIANG
;
Hanying ZHOU
Author Information
1. 西北妇女儿童医院生殖中心，西安 710000
- Publication Type:Journal Article
- Keywords:
Ovarian hyperstimulation syndrome;
Hyponatremia;
Brain edema;
Controlled ovarian hyperstimulation;
Oocyte retrieval
- From:
Chinese Journal of Reproduction and Contraception
2023;43(3):291-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the mechanism, treatment and prevention of brain edema after controlled ovarian hyperstimulation (COH) and transvaginal ovarian puncture and oocyte retrieval.Methods:A retrospective clinical study and literature review were performed to analyze one patient who was diagnosed as having brain edema after COH and transvaginal ovarian puncture and oocyte retrieval.Results:After long acting gonadotropin-releasing hormone analogue (GnRH-a) COH protocol, 30 oocytes were obtained. Hydroxyethyl starch 500 mL was given to treat ovarian hyperstimulation syndrome (OHSS) after oocyte retrieval. The patient had sudden irritability, blurred consciousness and vomiting at the 8th hour after oocyte retrieval. The examinations showed hyponatremia and brain edema. The patient relived after mannitol and hypertonic saline treatment. On the 5th day after oocyte retrieval, the patient performed paracentesis guided by ultrasound due to seroperitoneum. Low molecular weight heparin was applied to prevent thrombosis after the flare up of serum D-Dimer on the 7th day. The patient recovered and discharged after 2 weeks.Conclusion:The incidence of brain edema after COH and transvaginal ovarian puncture and oocyte retrieval was very low. However, the symptoms may be severe and may be life-threatening.
