Neuroimaging features of febrile infection-related epilepsy syndrome

VernacularTitle:发热感染相关癫痫综合征的神经影像学特点
Author: Xueyi RAO ¹ ; Xiaoqian WANG ¹ ; Jun CHEN ¹
Author Information

1. 610041 成都,四川大学华西第二医院儿科/出生缺陷与相关妇儿疾病教育部重点实验室·发育与妇儿疾病四川省重点实验室
Publication Type:Journal Article
Keywords: febrile infection-related epilepsy syndrome; epilepsy; neuroimaging
From: Journal of Clinical Neurology 2025;38(1):38-41
CountryChina
Language:Chinese
Abstract: Objective To investigate the neuroimaging features of febrile infection-related epilepsy(FIRES).Methods The FIRES studies containing MRI imaging data were searched in PubMed,Ovid Medline,Scopus,Cochrane Library,Embase,Web of Science,CNKI,Wanfang database and VIP database.The search timeframe covered studies from 1998 to the present.Results A total of 28 studies involving 143 patients were included.In the acute phase,most FIRES patients had normal cranial MRI scans,though some may exhibit abnormal signals in areas such as the temporal lobe and basal ganglia.As the disease progresses,chronic phase MRIs often show generalized brain atrophy and medial temporal lobe sclerosis.Conclusion Although the imaging manifestations of FIRES lack specificity,it is of great significance for the diagnosis and differential diagnosis of the disease to be familiar with and understand the common manifestations of head MRI in different periods of FIRES.