Effect of neuroendoscopy-assisted microsurgical vascular decompression under combined monitoring of abnormal muscle response and brainstem auditory evoked potential in the treatment of hemifacial spasm
- VernacularTitle:异常肌反应与脑干听觉诱发电位联合监测下神经内镜辅助显微血管减压术治疗偏侧面肌痉挛的临床效果
- Author:
Zhao ZHANG
1
;
Xiongwei LU
1
Author Information
- Publication Type:Journal Article
- Keywords: hemifacial spasm(HFS); microsurgical vascular decompression(MVD); neuroendoscopy; facial nerve function grading; electrophysiological parameters; quality of life; sleep quality; complication
- From: China Journal of Endoscopy 2025;31(8):68-77
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the effect of neuroendoscopy-assisted microsurgical vascular decompression(MVD)on hemifacial spasm(HFS)under the combined monitoring of abnormal muscle response(AMR)and brainstem auditory evoked potential(BAEP),and its impact on serum myelin basic protein(MBP)and neuron-specific enolase(NSE).Methods 110 patients with HFS from January 2019 to December 2023 were prospectively selected and divided into a control group(n=55)and study group(n=55)according to the random number table method.The control group received neuroendoscopy-assisted MVD treatment,while the study group received neuroendoscopy-assisted MVD treatment under the combined monitoring of AMR and BAEP.The therapeutic effects,the levels of serum MBP and NSE,facial nerve function grading,electrophysiological parameters of facial nerve(compound muscle action potential,blink reflex wave amplitude R1,R2,and R2'),quality of life[hemifacial spasm scale(HFS-8)score],and sleep quality[Pittsburgh sleep quality index(PSQI)score]before and after surgery,and complication rates of the two groups were compared.Results The total effective rate of the study group was 94.55%(52/55),which was higher than that of the control group(80.00%,44/55),the difference was statistically significant(P<0.05).At 1 and 3 d after operation,the levels of serum MBP and NSE in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).At 6 months after surgery,the facial nerve function grading of the study group was better than that of the control group,the blink reflex wave amplitudes R1,R2 and R2'were lower than those of the control group,and the compound muscle action potential was higher than that of the control group,the differences were statistically significant(P<0.05).At 6 months after surgery,the HFS-8 score and PSQI score of the study group were lower than those of the control group,the difference was statistically significant(P<0.05).The difference in the incidence rate of complications between the two groups was not statistically significant(P>0.05).Conclusion The combined monitoring of AMR and BAEP under neuroendoscopy-assisted MVD treatment of HFS patients has significant effects,improving patients'neurological function,improving their sleep quality and quality of life,and has high safety.
