Advances in Study on Detection of Helicobacter pylori Infection and Antibiotic Resistance Based on Gastric Juice Samples
10.3969/j.issn.1008-7125.2024.06.006
- VernacularTitle:基于胃液样本检测幽门螺杆菌感染和抗菌药物耐药性的研究进展
- Author:
Xiujuan WANG
1
;
Xuetian QIAN
1
;
Zhenyu ZHANG
1
Author Information
1. 南京医科大学附属南京医院(南京市第一医院)消化内科(210006)
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Gastric Juice;
Antibiotic Resistance;
Diagnosis
- From:
Chinese Journal of Gastroenterology
2024;29(6):352-356
- CountryChina
- Language:Chinese
-
Abstract:
Helicobacter pylori(Hp)infection is associated with multiple gastrointestinal diseases.With the increase of Hp antibiotic resistance,its eradication rate has been declining year by year.Performing antibiotic resistance testing before eradication can enhance the eradication rate of Hp.Current antibiotic resistance testing encompasses phenotypic and genotypic approaches.Phenotypic resistance testing based on Hp culture requires invasive endoscopic biopsies,strict culture conditions,and extended incubation periods,while genotypic resistance testing based on gastric juice samples offers a simpler,faster,and more sensitive alternative.This article reviewed the advances in study on the detection of Hp infection and antibiotic resistance based on gastric juice samples,with the goal of identifying more practical and efficient diagnostic strategies.
