The Value of Stroboscopic Laryngoscope Combined with Narrow Band Imaging Endoscope in Diagnosing the Benign and Malignant of Vocal Cord Hyperplastic Lesions
10.3969/j.issn.1006-7299.2025.01.004
- VernacularTitle:频闪喉镜联合窄带成像内镜对声带增生性病变良恶性的判断价值
- Author:
Dan XU
1
;
Zhiji CHEN
1
;
Xiaoguang LI
1
;
Guijun YANG
1
;
Hailan MO
1
;
Shitong ZHOU
1
;
Hongyan FANG
1
Author Information
1. 重庆市人民医院(重庆 400014)
- Publication Type:Journal Article
- Keywords:
Vocal cord hyperplastic lesions;
Stroboscopic laryngoscopy;
Narrowband imaging endoscopy
- From:
Journal of Audiology and Speech Pathology
2025;33(1):18-23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of stroboscopic laryngoscope combined with narrow band imaging endoscope in the diagnosis of benign and malignant glottic lesions.Methods A total of 60 patients(84 sides of vocal cord)who visited our department from June 2022 to January 2023 with hoarseness as the main complaint and were found to have glottic lesions by electronic nasopharyngoscopy were selected.In all 60 patients with 84 sides of vocal cord degenerative lesions,stroboscopic laryngoscopy and narrow band imaging(NBI)endoscopy were com-pleted.The examination results were evaluated and graded separately.The same operative group performed the re-section biopsy of vocal cord lesions under general anesthesia and laryngoscope respectively,and the pathological re-sults were used as the diagnostic gold standard.With sensitivity,specificity,accuracy,false negative rate,and false positive rate as the main evaluation indexes,the differences in diagnostic accuracy between single test technique and combined application of the two techniques were analyzed.Results Pathological results showed squamous cell carci-noma on 18 sides,carcinoma in situ on 4 sides,severe dysplasia on 4 sides,mild and moderate dysplasia on 13 sides,and papilloma,chronic,mucosal,nflammation,hyperplasia,hypokeratosis,hyperkeratosis on 45 sides.The sensitivity of strobe laryngoscopy detection was 53.06％and specificity was 60.34％.The sensitivity of NBI endo-scopic detection was 88.46％,and the specificity was 89.66％.The sensitivity of strobe laryngoscopy combined with NBI endoscopy was 96.15％,and the specificity was 94.83％.The areas under the ROC curve of strobe laryn-goscopy,NBI endoscopy and white light imaging combined with narrowband imaging were 0.888(95％CI:0.820～0.957),0.943(95％CI:0.885～1),0.970(95％CI:0.942～0.999),respectively.The area under the curve of the combined method was higher than that of the single method,and the difference was statistically significant(P＜0.05).Conclusion Stroboscopic laryngoscope combined with NBI endoscope can improve the diagnostic accuracy of benign and malignant glottic lesions.
