Research progress of pericytes and its prospect in gynaecology and obstetrics
10.3760/cma.j.cn101441-20210818-00362
- VernacularTitle:周细胞的研究现状及其在妇产科中的研究展望
- Author:
Zhao LIU
1
;
Baosheng HAN
;
Jinghua ZHANG
;
Xiujun ZHANG
Author Information
1. 华北理工大学公共卫生学院，唐山 063210
- Publication Type:Journal Article
- Keywords:
Pericytes;
Pregnancy;
Reproduction;
Capillary permeability;
Embryo implantation;
Decidualization;
Uterus
- From:
Chinese Journal of Reproduction and Contraception
2022;42(11):1192-1198
- CountryChina
- Language:Chinese
-
Abstract:
Pericytes are microvascular mural cells surrounding the endothelial cells of capillaries. Pericytes play a critical role in various diseases by regulating vascular morphology and function, such as diabetic retinopathy, Alzheimer's disease, hemorrhagic stroke, tissue fibrosis and tumor metastasis. Moreover, pericytes are mesenchymal progenitor cells that can differentiate into fibroblasts, vascular smooth muscle cells, adipose cells, cartilage, bone, and muscle. There are few studies on pericytes during pregnancy, and some existing evidence points to pericytes playing an essential role in some aspects of pregnancy. In this paper, the research progress of pericytes was reviewed, and the future research direction of uterine pericytes was prospected.
