Research progress on the mechanism of abnormal endometrial receptivity in women with polycystic ovary syndrome
10.3760/cma.j.cn101441-20211217-00561
- VernacularTitle:多囊卵巢综合征患者子宫内膜容受性异常机制研究
- Author:
Hongying SHAN
1
;
Ping ZHOU
1
;
Rong LI
1
Author Information
1. 北京大学第三医院妇产科生殖医学中心，北京 100191
- Publication Type:Journal Article
- Keywords:
Polycystic ovary syndrome;
Endometrial receptivity;
Abnormal mechanism
- From:
Chinese Journal of Reproduction and Contraception
2023;43(4):412-417
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of childbearing age. Its etiology is complex and its clinical manifestations are highly heterogeneous. Poor endometrial receptivity is an important reason for pregnancy failure after PCOS ovulation induction in spite of high ovulation rate. This paper reviewed the relationship between endometrial receptivity and abnormal mechanisms such as oxidative stress, chronic low-grade inflammation, metabolic abnormalities, endocrine disorders and endometrial hormone receptors in order to provide theoretical reference for clinicians to diagnose and treat PCOS women involving the endometrial receptivity.
