Effect of sexual abstinence on semen analysis parameters in oligospermia and asthenozoospermia
10.3760/cma.j.cn101441-20210611-00263
- VernacularTitle:禁欲时间对少精子症和弱精子症精液参数的影响
- Author:
Yelin JIA
1
;
Fuping LI
Author Information
1. 四川大学华西第二医院人类精子库/生殖男科，成都 610061
- Publication Type:Journal Article
- Keywords:
Sexual abstinence;
Semen analysis;
Oligospermia;
Asthenozoospermia;
Semen parameters
- From:
Chinese Journal of Reproduction and Contraception
2022;42(7):696-702
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the impact of sexual abstinence (SA) on semen parameters in oligospermia and asthenozoospermia.Methods:This retrospective cohort study was conducted for the clinical data from oligospermia ( n=5127), asthenozoospermia ( n=4003) and normozoospermia ( n=4529) with different SAs (2 d,3 d,4 d,5 d,6 d,7 d) who were treated in Andrology Department of West China Second University Hospital during January 2018 to December 201 9. The correlation between semen parameters (sperm concentration, motility, total motile sperm count etc.) and SA were observed. Results:In normozoospermia, as the SA was getting longer, the semen volume was increased from (3.3±1.2) mL to (4.1±1.3) mL ( r=0.167, P<0.001), the sperm concentration was increased from (89.0±60.9)×10 6/mL to (125.2±82.3)×10 6/mL ( r=0.181, P<0.001), the total sperm count was increased from (273.2±169.8)×10 6/ejaculate to (473.5±193.7)×10 6/ejaculate ( r=0.310, P<0.001). The progressive motility was decreased from 62.1%±13.0% to 59.5%±13.3% ( r=-0.057, P<0.001). The viability was decreased from 80.6%±8.5% to 79.0%±9.1% ( r=-0.048, P<0.001). In oligospermia, the semen volume was increased from (3.1±1.4) mL to (3.9±1.6) mL ( r=0.171, P<0.001) and the sperm concentration was decreased from (10.3±5.5)×10 6/mL to (8.7±4.3)×10 6/mL ( r=-0.043, P<0.001), the total sperm count was increased from (29.0±17.1)×10 6/ejaculate to (38.6±19.8)×10 6/ejaculate ( r=0.285, P<0.001). The progressive motility was decreased from 41.1%±17.0% to 35.1%±17.3% ( r=-0.141, P<0.001). The viability was decreased from 71.1%±12.3% to 63.1%±16.6% ( r=-0.225, P<0.001). The peak value of sperm concentration and motility were observed on day 2. In asthenozoospermia, the semen volume was increased from (3.1±1.4) mL to (3.8±1.9) mL ( r=0.197, P<0.001) and the sperm concentration was increased from (35.1±30.5)×10 6/mL to (49.7±31.9)×10 6/mL ( r=0.071, P<0.001), the total sperm count was increased from (109.1±82.3)×10 6/ejaculate to (170.1±99.3)×10 6/ejaculate ( r=0.394, P<0.001). The viability was decreased from 59.6%±16.4% to 54.0%±16.4% ( r=-0.081, P<0.001). The SA was not related to motility and round cells ( P>0.05). TMSC was slightly increased with extending EAT ( r=0.119, P<0.001). Conclusion:The longer SA has positive influence on semen volume and total sperm count on different levels in males with normozoospermia, oligospermia and asthenozoospermia. The viability was decreased by extended SA. Shortening the SA was likely to help oligospermic patients conduct sperm with higher concentration, motility, viability and normal morphology. TMSC was not significantly increased by extended SA. Asthenozoospermia can conduct sperm with higher concentration and TMSC when applying longer SA. The progressive motility was not significantly influenced by SA.
