Clinical characteristics and influencing factors for prognosis of patients with bloodstream infection caused by Stenotrophomonas maltophilia
10.12138/j.issn.1671-9638.20256987
- VernacularTitle:嗜麦芽窄食单胞菌血流感染患者的临床特征及预后影响因素
- Author:
Tingting ZHOU
1
;
Huicang LIANG
1
;
Renli QIN
1
;
Yu LU
1
Author Information
1. 柳州市人民医院检验科 柳州市病毒性疾病精准医学重点实验室 广西壮族自治区卫生健康委员会广西临床疾病生物技术研究重点实验室,广西柳州 545006
- Publication Type:Journal Article
- Keywords:
Stenotrophomonas maltophilia;
bloodstream infection;
healthcare-associated infection;
clinical cha-racteristics;
prognosis
- From:
Chinese Journal of Infection Control
2025;24(1):127-132
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics and influencing factors for prognosis of patients with bloodstream infection(BSI)caused by Stenotrophomonas maltophilia(S.maltophilia).Methods Clinical data of patients with S.maltophilia BSI in Liuzhou People's Hospital from January 2019 to December 2023 were retro-spectively analyzed.Patients were divided into good prognosis group and poor prognosis group according to their prognosis.Risk factors for poor prognosis were analyzed by univariate analysis and binary logistic regression analy-sis.Results From 2019 to 2023,a total of 36 patients were diagnosed with S.maltophilia BSI,with an average age of(51.8±22.6)years.The most common clinical symptom was fever(91.7％),followed by respiratory symp-toms(25.0％).33 patients(91.7％)had underlying diseases,31 patients(86.1％)had healthcare-associated in-fection,and 23 patients(63.9％)underwent invasive procedures before onset.Among the 36 patients with S.mal-tophilia BSI,12(33.3％)had a poor prognosis.Univariate analysis showed that underlying blood diseases,length of hospital stay ≥30 days,agranulocytosis,and elevation of C-reactive protein(CRP)were related to poor progno-sis of patients with S.maltophilia BSI(all P＜0.05).Binary logistic regression analysis results showed that underlying blood diseases,length of hospital stay ≥30 days,and agranulocytosis were independent risk factors for poor prognosis in patients(all P＜0.05).Conclusion Patients with S.maltophilia BSI are critically ill with high mortality.Underlying blood diseases,length of hospital stay ≥30 days,and agranulocytosis are independent risk factors for poor prognosis in patients.
