Catheter-associated and non-catheter-associated urinary tract infection in hospitalized patients in Suzhou City:a multicenter study on epidemiologi-cal characteristics
10.12138/j.issn.1671-9638.20252254
- VernacularTitle:苏州市住院患者导尿管相关和非导尿管相关尿路感染多中心流行病学特征研究
- Author:
Jingxue LIU
1
;
Xiuzhen WANG
;
Meizhen QIAO
;
Junji ZHANG
;
Wei DING
;
Shu-kai ZHU
;
Meijuan JIN
;
Xiaochao SONG
Author Information
1. 苏州大学附属第四医院(苏州市独墅湖医院)感染管理科,江苏苏州 215127
- Publication Type:Journal Article
- Keywords:
catheter-associated urinary tract infection;
non-catheter-associated urinary tract infection;
healthcare-associated infection;
antimicrobial resistance;
surveillance
- From:
Chinese Journal of Infection Control
2025;24(8):1056-1065
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the epidemiological characteristics and differences in antimicrobial resistance be-tween catheter-associated urinary tract infection(CAUTI)and non-CAUTI of healthcare-associated infection(HAI),and provide scientific basis for precise clinical prevention and control.Methods Based on the regional HAI surveillance platform in Suzhou City,urinary tract infection(UTI)surveillance data reported by 61 member units from January 2020 to December 2024 were analyzed retrospectively.Pathogen distribution,detection rate of multi-drug-resistant organisms(MDROs),and antimicrobial resistance spectrum characteristics of patients in the CAUTI group and non-CAUTI group were compared.Results The incidence of CAUTI in patients in CAUTI group was 0.99‰,the incidence of healthcare-associated UTI in patients in non-CAUTI group was 0.14％.There was statis-tically significant difference in the distribution of UTI pathogens between the two groups(P＜0.05).The patho-gens of the CAUTI group were mainly Gram-negative bacteria(56.1％),with high proportions of Escherichia coli(19.6％)and Klebsiella pneumoniae(15.0％).In the non-CAUTI group,the proportion of Gram-negative bacteria was higher(64.7％).Antimicrobial susceptibility testing results showed that the resistance rates of Escherichia co-li to tobramycin,cephalosporins,and carbapenems in the CAUTI group were all higher than those in the non-CAU-TI group(all P＜0.05).Except for tigecycline,the resistance rates of Klebsiella pneumoniae to other antimicrobial agents in the CAUTI group were all significantly different from the non-CAUTI group(all P＜0.05).The resis-tance rates of Acinetobacterbaumannii to ticarcillin/clavulanic acid,quinolones,most cephalosporins,carbapenems,and aminoglycosides in the CAUTI group were higher than those of the non-CAUTI group(all P＜0.05).The de-tection rates of MDROs were higher in the CAUTI group,especially that of carbapenem-resistant Klebsiella pneu-moniae,accounting for 57.8％.Conclusion There are significant differences in pathogen distribution and antimi-crobial resistance of UTI between the CAUTI group and the non-CAUTI group.It is necessary to establish a re-gional antimicrobial resistance surveillance system for pathogens in UTI,and provide basis for the rational use of an-timicrobial agents in clinical practice.
