Research progress on the relationship between mitochondrial function and polycystic ovary syndrome
10.3760/cma.j.cn101441-20210815-00354
- VernacularTitle:线粒体功能与多囊卵巢综合征关系的研究进展
- Author:
Yuanyue ZHANG
1
;
Ruihong MA
1
;
Tian XIA
1
Author Information
1. 天津中医药大学第一附属医院 国家中医针灸临床医学研究中心，天津 300193
- Publication Type:Journal Article
- Keywords:
Mitochondria;
Polycystic ovary syndrome;
Oxidative stress;
Hyperandrogenism;
Insulin resistance;
Ovarian follicle
- From:
Chinese Journal of Reproduction and Contraception
2022;42(12):1305-1309
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine and metabolic disorder. Studies have found that patients with PCOS are often accompanied by mitochondrial dysfunction. When the mitochondrial function is abnormal, the level of oxidative stress increases, which can cause or aggravate hyperandrogenemia, insulin resistance and obesity, interfere with follicular development, and then affect the menstrual and reproductive functions of women with PCOS. Mitochondrial function has been a hot topic in recent years. This article summarizes the research progress of the potential mechanism of mitochondrial dysfunction in the occurrence and development of PCOS.
