Current situation of the first-visit infertile couples in assisted reproductive institutions in Beijing, Tianjin and Hebei Province in China: a cross-sectional study
10.3760/cma.j.cn101441-20210926-00431
- VernacularTitle:京津冀地区辅助生殖机构不孕不育首诊育龄夫妇现况分析
- Author:
Tian TIAN
1
;
Rui YANG
;
Jia LI
;
Dongying WANG
;
Yanjun FAN
;
Yuanyuan WANG
;
Rong LI
;
Hongzhen LI
;
Ping LIU
;
Jie QIAO
Author Information
1. 北京大学第三医院妇产科生殖医学中心 国家妇产疾病临床医学研究中心 辅助生殖教育部重点实验室 北京市生殖内分泌与辅助生殖技术重点实验室，北京 100191
- Publication Type:Journal Article
- Keywords:
Cross-sectional study;
Fertility;
Reproductive technology, assisted;
Ovarian reserve
- From:
Chinese Journal of Reproduction and Contraception
2022;42(12):1265-1273
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the current situation of infertile couples in reproductive institutions in Beijing, Tianjin, and Hebei Province in China, thus providing clues for the optimal allocation of assisted reproductive medical resources.Methods:Based on a cross-sectional design, the information of 10 159 first-visit infertile couples from representative assisted reproductive centers in Beijing, Tianjin, and Shijiazhuang in Hebei Province was extracted from the national monitoring platform for couples with low fertility. The basic characteristics, lifestyle information, assisted reproductive technology (ART) treatment information, and biological indicators of couples were investigated. Both of the regional and age distributions of those characteristics were analyzed.Results:The childless rate of the infertility population reached more than 80%. In Beijing, the rates of provincial patients [66.5% (1285/1934)], first marriage [91.7% (3326/3626)], and age≥43 years [3.3% (142/4331)] were significantly higher than those in Tianjin [11.9% (276/2381), 90.8% (2191/2412), 2.5% (101/4045)] and Shijiazhuang city [4.7% (77/1628), 86.0% (1533/1783), 1.5% (27/1783), all P<0.001]. The patients in Beijing had higher follicle-stimulating hormone (FSH) level and lower anti-Müllerian hormone (AMH) level [the rate of FSH>10 U/L: 8.9% (361/4077) and the rate of AMH<1.1 μg/L: 26.8% (602/2249)] than those in Tianjin [5.3% (202/3828), 25.8% (455/1763)] and Shijiazhuang in Hebei Province [6.9% (115/1666), 15.7% (269/1712), all P<0.05]. With the increasing of age, FSH level increased (the rates of FSH>10 U/L increased from 0% at 20 years old to 67.7% at 49 years old, AMH and AFC decreased (the rate of AMH<1.1 μg/L increased from 0% at 20 years old to 100% at 49 years old; and the rate of AFC<5 increased from 11% at 20 years old to 100% at 49 years old). Conclusion:The composition of first-visit infertility patients in Beijing, Tianjin, and Hebei Province are different. In the process of assisted reproductive resource allocation, the social needs, local conditions, the reasonably hierarchical diagnosis and treatment system should be fully considered.
