Pay attention to the proper application of epinephrine in anaphylaxis
10.3760/cma.j.cn114015-20230828-00640
- VernacularTitle:关注严重过敏反应中肾上腺素的正确应用
- Author:
Ziran NIU
1
;
Zixi WANG
;
Bo ZHANG
Author Information
1. 中国医学科学院北京协和医学院北京协和医院药剂科,疑难重症及罕见病国家重点实验室,北京 100730
- Publication Type:Journal Article
- Keywords:
Anaphylaxis;
Shock;
Epinephrine;
Emergency treatment;
Adrenaline autoinjectors
- From:
Adverse Drug Reactions Journal
2023;25(9):517-520
- CountryChina
- Language:Chinese
-
Abstract:
Anaphylaxis is a severe, life-threatening, immediate, and systemic allergic reaction, and may lead to serious consequences due to delayed diagnose or improper treatment. Guidelines at home and abroad recommend epinephrine as a first-line treatment for anaphylaxis. But there are still some problems such as insufficient use, inappropriate administration route or dosage of epinephrine in the treatment of anaphylaxis in China. The timing (as early as possible), route (intramuscular injection is preferred), and dosage of epindphrine should strictly follow the recommendations of relevant guidlines. Epinephrine autoinjectors can win more rescue time for patients with anaphylaxis, and can be equipped and used after training by clinicians.