Stem cell therapy in the treatment of premature ovarian failure
10.3760/cma.j.cn101441-20200901-00471
- VernacularTitle:干细胞治疗早发性卵巢功能不全的研究进展
- Author:
Xu LUAN
1
;
Xiaodan LU
;
Xuguang MI
;
Xiuying LIN
;
Mengxue WU
;
Meiling FAN
;
Yanqiu FANG
Author Information
1. 长春中医药大学临床医学院 130021
- Publication Type:Journal Article
- Keywords:
Premature ovarian insufficiency;
Stem cells;
Granulosa cells
- From:
Chinese Journal of Reproduction and Contraception
2021;41(11):1031-1035
- CountryChina
- Language:Chinese
-
Abstract:
Premature ovarian insufficiency has become a major problem that plagues women of childbearing age. So far, there is no effective treatment method. Stem cells have the potential for self-renewal and multidirectional differentiation, and are increasingly being considered for the treatment of ovarian insufficiency. Stem cells extracted from bone marrow, umbilical cord, peripheral blood, and amniotic fluid can migrate to the ovary and proliferate, differentiate and mature in a specific ovarian environment, secrete related factors, promote ovarian function repair, and increase the quality of ovarian follicles and the number of granulosa cells at all levels. Improve endocrine function and restore fertility to a certain extent. This article reviews the research progress of various types of stem cells in the treatment of premature ovarian insufficiency.
