Research progress of exocrine in endometriosis

VernacularTitle:外泌体在子宫内膜异位症中的研究进展
Author: Xin XIN ¹ ; Fang LIAN ; Haicui WU
Author Information

1. 山东中医药大学，济南250011
Publication Type:Journal Article
Keywords: Endometriosis; Exosome; Diagnostic markers; Treatment
From: Chinese Journal of Reproduction and Contraception 2021;41(10):915-919
CountryChina
Language:Chinese
Abstract: Endometriosis (EMS) is a common and frequently-occurring disease in gynecology, which has the characteristics of strong invasiveness, wide range of lesions and easy recurrence. However, its pathogenesis is not clear. Exocrine bodies are microvesicles that widely exist in a variety of body fluids and cells, and have the functions of secretion, uptake and transport. This paper summarized the related studies of exosomes and their non-coding RNA in EMS, and their roles in cell proliferation and apoptosis, intimal migration, angiogenesis and fibrosis in the occurrence and development of EMS. Exosomes may become a non-invasive diagnostic markers of EMS with high specificity, sensitivity and accuracy, which provide ideas for clinical targeted therapy of EMS in the future.