Research advances in C-type lectin receptors DC-SIGN in influenza viral infections
10.3969/j.issn.1000-484X.2025.02.034
- VernacularTitle:C型凝集素受体DC-SIGN及其在流感病毒感染中的研究进展
- Author:
Yeqing TU
1
;
Rui ZHENG
;
Deyan LUO
;
Hui WANG
Author Information
1. 军事科学院军事医学研究院微生物流行病研究所病原微生物生物安全国家重点实验室,北京 100071
- Publication Type:Journal Article
- Keywords:
C-type lectins;
DC-SIGN(CD209);
Influenza viral infection
- From:
Chinese Journal of Immunology
2025;41(2):456-460
- CountryChina
- Language:Chinese
-
Abstract:
C-type lectin receptors DC-SIGN is a transmembrane protein that mainly express on dendritic cell surface and its carbohydrate recognition domain can be combined with a variety of pathogens.In recent years,with deepening of research on viral infection immunity,multifaceted role played by DC-SIGN is gradually being mined.As a kind of pattern recognition molecules,DC-SIGN plays a crucial part in both innate and adaptive immune response,and can be mediated cis and trans viral infections.Starting with structure,function,expression and ligand of DC-SIGN,this review introduces molecular homologue in different species and finally summarizes role of DC-SIGN in influenza virus infections,which in order to find a new idea to study and treatment of viral infections associated with DC-SIGN.
