Analysis of TORCH screening results of 330 115 reproductive-age females who underwent pre-pregnancy health examination in Shenzhen
10.3760/cma.j.cn101441-20200615-00346
- VernacularTitle:深圳市330 115例孕前优生健康检查育龄女性TORCH筛查结果分析
- Author:
Juan YANG
1
;
Yue ZHANG
;
Dongmei ZHANG
;
Xuhuai HU
;
Weiwei LIN
;
Qiaoyun DAI
;
Cao LU
;
Jun ZHAO
;
Ting GUAN
Author Information
1. 深圳市卫生健康发展研究和数据管理中心 518028
- Publication Type:Journal Article
- Keywords:
Toxoplasma;
Rubella virus;
Cytomegalovirus;
Preconception care;
Reproductive-age females
- From:
Chinese Journal of Reproduction and Contraception
2021;41(11):1011-1018
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the results of TORCH screening for reproductive-age females who underwent pre-pregnancy health examination in Shenzhen to guide scientific pregnancy preparation.Methods:Cross-sectional study was performed on the TORCH screening results of 330 115 reproductive-age females who participated in free pre-pregnancy health examination in Shenzhen from January, 2013 to December, 2019. The χ2 test was used to analyze the differences of TORCH screening results among reproductive-age females in different years, administrative regions and demographic characteristics. Results:The overall positive rates of screening for rubella virus (RV)-IgG, cytomegalovirus (CMV)-IgG, CMV-IgM, toxoplasma gondii (TOX)-IgG and TOX-IgM among reproductive-age females in Shenzhen were 85.54% (282 377/330 115), 96.36% (318 088/330 115), 0.31% (1009/330 115), 3.12% (10 292/330 115) and 0.64% (2114/330 115), respectively. Compared with 2013 to 2016, the average positive rates of RV-IgG and CMV-IgG among reproductive-age females in Shenzhen increased ( P=0.003, P<0.001), while the average positive rates of TOX-IgG and TOX-IgM decreased from 2017 to 2019 ( P<0.001). There were statistically significant differences in the positive rates of the five antibodies among different administrative regions (all P<0.001). Except for the differences in the positive rates of CMV-IgM and TOX-IgM among women of different ages, there were statistically significant differences in the positive rates of these five antibodies among reproductive-age females with other demographic characteristics (all P<0.05). There were statistical differences in the positive rates of TORCH antibodies among women with different demographic characteristics in different years. Conclusion:Compared with 2013 to 2016, the positive rates of RV-IgG and CMV-IgG in reproductive-age females in Shenzhen from 2017 to 2019 were on the rise, while the positive rates of TOX-IgG and TOX-IgM were on the decline. The positive rates of these five antibodies were different among different administrative regions and among reproductive-age females with different demographic characteristics, which suggested that plans should be made according to local conditions and different objects in order to strengthen the awareness of eugenics and reduce the risk of congenital intrauterine infection with TORCH of the fetus during the propaganda and education of eugenics.
