Structural MRI radiomics model for diagnosing the cerebral damage following carbon monoxide poisoning
10.3969/j.issn.1002-1671.2025.08.001
- VernacularTitle:一氧化碳中毒脑损伤的结构MRI影像组学诊断模型
- Author:
Junxia XU
1
;
Yanli ZHANG
;
Tianhong WANG
;
Junqiang LEI
Author Information
1. 兰州大学第一临床医学院,甘肃 兰州 730000;甘肃省中医院放射影像科,甘肃 兰州 730050
- Publication Type:Journal Article
- Keywords:
carbon monoxide poisoning;
white matter;
gray matter;
magnetic resonance imaging;
radiomics
- From:
Journal of Practical Radiology
2025;41(8):1257-1261
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct an MRI radiomics model of cerebral damage following carbon monoxide(CO)poisoning.Methods Ninety patients with CO poisoning and 70 healthy controls(HC)were scanned by structural MRI.All patients were randomly divided into training set(n=128)and test set in a ratio of 8∶2.The radiomics features of 9 regions of interest(ROI)were automatically extracted,and each ROI was subjected to 5-fold cross-validation and 9 different types of classifiers to construct a diagnostic model.Receiver operating characteristic(ROC)curve and decision curve analysis(DCA)were used to evaluate the diagnostic efficacy and clinical value of the model.Results The model based on the radiomics features of the whole brain gray matter(GM)and the left globus pallidus(LGP)had better diagnostic efficacy and clinical application value.The area under the curve(AUC)in the training set and the test set were 0.813,0.815 and 0.806,0.806,respectively.Conclusion The GM-based radiomics model can effectively diagnose cerebral damage following CO poisoning.
