Research progress on neuropsychiatric comorbidities in childhood absence epilepsy
10.3969/j.issn.1004-1648.2025.04.022
- VernacularTitle:儿童失神癫痫的神经精神共患病研究进展
- Author:
Yinjie ZHU
1
;
Xiaoshan WANG
1
Author Information
1. 210029 南京医科大学附属脑科医院神经内科
- Publication Type:Journal Article
- Keywords:
childhood absence epilepsy;
comorbidity;
attention deficit hyperactivity disorder;
mood disorders;
cognitive dysfunction
- From:
Journal of Clinical Neurology
2025;38(4):311-317
- CountryChina
- Language:Chinese
-
Abstract:
Childhood absence epilepsy(CAE)is a common pediatric epilepsy syndrome traditionally considered benign.However,an increasing body of research indicates that children with CAE often present with comorbid neuropsychiatric disorders such as attention deficit hyperactivity disorder,mood disorders,and cognitive dysfunction.These comorbidities not only impair the children's academic performance and social adaptability but also negatively affect their psychological well-being and quality of life.However,the symptoms of these comorbidities are often subtle,and there is a lack of standardized assessment criteria and treatment strategies,making their diagnosis and long-term management a persistent challenge in clinical practice.This review aims to summarize the latest research progress on the comorbidities of CAE,focusing on the types and clinical characteristics of these comorbidities,influencing factors,diagnostic approaches,and treatment strategies,to enhance understanding of CAE comorbidities and provide reference for future research and clinical management.