The mediating effect of protracted abstinence duration and impulsivity in heroin addicts
10.3969/j.issn.1002-1671.2025.08.003
- VernacularTitle:海洛因成瘾者强制戒断治疗时间与冲动性的中介效应
- Author:
Nannan CAO
1
;
Jiajie CHEN
;
Zhidong WANG
;
Liyang DANG
;
Jia ZHU
;
Yongbin LI
;
Wei WANG
Author Information
1. 空军军医大学唐都医院放射科,陕西 西安 710038
- Publication Type:Journal Article
- Keywords:
heroin addiction;
protracted abstinence treatment;
impulsivity;
GO/NOGO task;
mediating effect
- From:
Journal of Practical Radiology
2025;41(8):1267-1270
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of the duration of protracted abstinence(PA)treatment on the level of impulsivity among heroin addicts and to analyze the mediating effect of impulsive cognition between abstinence duration and impulsive behavior.Methods Thirty-six heroin addicts undergoing PA treatment(PA group)and forty matched healthy controls(HC)(HC group)were recruited.Demographic information was collected via questionnaires,and impulsive cognition assessments were conducted.Participants completed the GO/NOGO task to collect data on impulsive behavior.Intergroup differences were compared using the independent sample t-test,and multiple linear regression analysis and mediating effect analysis were performed on the PA group.Results The PA group exhibited significantly higher scores on motor impulsivity,non-planning impulsivity,and total impulsivity compared to the HC group.Additionally,the PA group demonstrated significantly increased NOGO error rate during the GO/NOGO task compared to the HC group(P＜0.001).Multiple linear regression analysis revealed that abstinence duration had a significant negative impact on total impulsivity and non-planning impulsivity(P＜0.001).Mediating effect analysis found a partial mediation effect of total impulsivity between abstinence duration and NOGO error rate(P＜0.001).Conclusion The PA treatment has a significant impact on the level of impulsivity among heroin addicts.Impulsive cognition play a partial mediating role between abstinence duration and impulsive behavior.These results provide an important theoretical and practical basis for optimizing PA treatment programs.
