Research progress of chronic endometritis in embryo implantation

VernacularTitle:慢性子宫内膜炎在胚胎植入中的研究进展
Author: Qijun XIE ¹ ; Chun ZHAO ¹ ; Xiufeng LING ¹
Author Information

1. 南京医科大学附属妇产医院生殖中心210004
Publication Type:Journal Article
Keywords: Endometritis; Infertility; Recurrent implantation failure; Recurrent spontaneous abortion; Hysteroscopy
From: Chinese Journal of Reproduction and Contraception 2021;41(10):898-904
CountryChina
Language:Chinese
Abstract: Chronic endometritis (CE) is a chronic persistent endometrial inflammation with no obvious clinical symptoms. It is mainly characterized by plasma cell infiltration in endometrial stroma and is mainly diagnosed by CD138 immunohistochemistry and hysteroscopy. Studies have found that CE affects the decidualization of endometrium and the expression of immune cells and cytokines, which is not conducive to embryo implantation, and is related to recurrent spontaneous miscarriage and repeated implantation failure. The main treatment of CE is antibiotic treatment. In recent years, endometrial mechanical stimulation and intrauterine perfusion have also become new methods for the treatment of CE.