Thoughts on research and development of female contraceptives from the perspective of pharmaceutics
10.3760/cma.j.cn101441-20210601-00250
- VernacularTitle:基于药剂学视角的女性避孕节育药具研发的思考
- Author:
Jia ZENG
1
;
Fang LI
1
;
Jianxing CHEN
1
;
Liangkang CHEN
1
;
Linglin FENG
1
Author Information
1. 上海市生物医药技术研究院，国家卫生健康委员会计划生育药具重点实验室，上海 生殖健康药具工程技术研究中心 200032
- Publication Type:Journal Article
- Keywords:
Contraception;
Long-acting preparation;
Biodegradable;
Microsphere;
Implant;
Frontier technologies
- From:
Chinese Journal of Reproduction and Contraception
2021;41(8):731-738
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the world community has aroused interest in family planning as a prioritized strategy to improve maternal health, and China has also incorporated reproductive health into its national development strategies. Safe and effective contraceptive methods for women of childbearing age to prevent unwanted pregnancy and reduce abortion, is an important measure to improve their reproductive health. This paper firstly summarizes the global market demand for female contraceptive products. Then, starting from the early research and development (R&D) stages such as raw materials selection, pre-formulation and formulation investigations, this paper discusses the R&D thoughts of contraceptives including long-acting biodegradable implants and microsphere injections. Finally, we review the application prospects of 3D printing, computer simulation and artificial intelligence in this field. Interdisciplinary integration of pharmaceutical and computer science is expected to inspire and change the development mode of traditional preparations, as well as to help accelerate the industrialization of contraceptives.
