Role and mechanism of lncRNA MIAT in inflammatory of disease
10.3969/j.issn.1000-484X.2025.01.035
- VernacularTitle:lncRNA MIAT在疾病炎症反应中的作用及机制
- Author:
Mingyue TIAN
1
;
Wanting MENG
1
;
Wanting QIN
1
;
Jing ZHU
1
;
Shuijin SHAO
1
Author Information
1. 上海中医药大学中西医结合学院人体解剖教研室,上海 201203
- Publication Type:Journal Article
- Keywords:
lncRNA MIAT;
Inflammation;
Molecular target;
Research progress
- From:
Chinese Journal of Immunology
2025;41(1):226-230
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNA myocardial infarction related transcript(MIAT)is a widely studied lncRNAs,which is closely related to the occurrence and development of many diseases.MIAT is associated with inflammatory responses in a variety of dis-eases through further exploring,including diabetes and its complications,cardiovascular and osteoarticular diseases.However,sys-tematic knowledge of the relationship between MIAT molecules and inflammation in diseases remains unclear.This article will focus on the relationship between MIAT and inflammation in various systemic diseases,especially its role,mechanism and potential clinical ap-plication as a biomarker and therapeutic target of disease inflammation,in order to provide molecular strategies for diagnosis and treat-ment of the inflammatory diseases.
