Extracorporeal membrane oxygenation for pediatric septic shock：rescue therapy or the window forward?
10.3760/cma.j.issn.1673-4912.2025.05.001
- VernacularTitle:儿童脓毒性休克体外膜肺氧合治疗：挽救性治疗还是窗口前移？
- Author:
Yun CUI
1
;
Yijun SHAN
1
;
Yucai ZHANG
1
Author Information
1. 上海市儿童医院 上海交通大学医学院附属儿童医院重症医学科 200062
- Publication Type:Journal Article
- Keywords:
Extracorporeal membrane oxygenation;
Refractory septic shock;
Rescue therapy;
Treatment timing;
Children
- From:
Chinese Pediatric Emergency Medicine
2025;32(5):321-325
- CountryChina
- Language:Chinese
-
Abstract:
The standard therapy bundle for septic shock includes antibiotics,fluid resuscitation,vasopressors and inotropes. Given the high mortality rates associated with septic shock,there is an ongoing need for active research into potential therapies to improve outcomes. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is an acceptable and beneficial therapeutic modality for patients who fail conventional management and have decreased left ventricular ejection fraction. Up to now,the benefits of ECMO in pediatric sepsis remain unclear. Whether ECMO is the rescue therapy or is appropriately utilized in the early stage (window forward) remains controversial. At the present stage,it is necessary to strictly screen patients and make individualized decisions based on dynamic hemodynamic monitoring and biomarkers.
