The Initial Evaluation of the Safety and Impact on Cardiac Electrical Synchronization Post Low Ventricular Septum Implantation of Leadless Pacemaker
10.3969/j.issn.1000-3614.2025.01.008
- VernacularTitle:无导线起搏器低位间隔植入对心脏电学同步性的影响及安全性初步评价
- Author:
Jifang MA
1
;
You ZHOU
1
;
Yonghui ZHAO
1
;
Haitao YANG
1
;
Xiaobiao ZANG
1
;
Juan HU
1
;
Weifeng SONG
1
;
Xianqing WANG
1
;
Haixia FU
1
Author Information
1. 国家心血管病中心华中分中心 河南心血管病中心 阜外华中心血管病医院 郑州大学华中阜外医院 心内科,郑州 450046
- Publication Type:Journal Article
- Keywords:
lead less pacemaker;
sick sinus syndrome;
atrioventricular block;
myocardial perforation;
electrical synchrony
- From:
Chinese Circulation Journal
2025;40(1):69-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aims to investigate the feasibility and safety of implanting leadless pacemakers in the low septum and its impact on cardiac electrical synchronization.Methods:A total of 36 patients who received leadless pacemaker implantation at Fuwai Central China Cardiovascular Hospital from January 2021 to August 2023 were included in this study.According to implantation sites of leadless pacemakers,patients were divided into mid-septal group(n=16)and low-septal group(n=20).The clinical characteristics and cardiac electrical synchronization were compared between the two groups.Results:There were 21 male patients,mean age was(68±13)years old.There was no statistical difference in the type of brady-arrhythmia between the two groups(P=0.73).There were 61 implant attempts in these 36 patients,and there was no significant difference in the number of attempts,procedure time,and pacemaker parameters between the two groups,but the average procedure time tended to be shorter in the low-septal group([84±37]minutes vs.[105±35]minutes,P=0.09).In terms of electrical synchronization,there was no statistical difference in QRS duration between the low-septal group and the mid-septal group([162.0±21.1]ms vs.[174.0±14.8]ms,P=0.20).There were no vascular puncture complications,cardiac perforation,or pericardial tamponade during the procedure.There were no complications and readmissions related to the leadless pacemaker during follow-up period.Conclusions:Our results show that the implantation of a leadless pacemaker in the low ventricular septum is safe and effective,has a similar impact on cardiac electrical synchronization as mid-septal pacing.