Clinical index of endometrial receptivity in assisted reproductive therapy
10.3760/cma.j.cn101441-20200226-00086
- VernacularTitle:辅助生殖治疗中子宫内膜容受性评估相关临床指标的研究进展
- Author:
Wanyi XIE
1
;
Rong LI
1
Author Information
1. 北京大学第三医院妇产科生殖医学中心 100191
- Publication Type:Journal Article
- Keywords:
Reproductive technology, assisted;
Recurrent implantation failure;
Endometrial receptivity;
Ultrasound;
Molecular marker
- From:
Chinese Journal of Reproduction and Contraception
2021;41(5):413-418
- CountryChina
- Language:Chinese
-
Abstract:
Although there has been exponential progress in the assisted reproductive technology (ART) in recent years, the clinical pregnancy rate of single embryo transfer hovers between 30%-40%. Recurrent implantation failure, which is mainly affected by the endometrial receptivity and the quality of the embryo, has been an important problem for patients and clinicians. Therefore, how to evaluate the endometrial receptivity objectively and appropriately has become a concern. In this review, the current relative factors of endometrium in different aspects are summarized from many studies, including clinical index, morphological characteristics, cytokines, different kinds of receptors and endometrial receptivity array. The current clinical application of various evaluation methods and their predictive function on the outcome of ART were summarized and analyzed. This review aims to help clinicians to make better assessment of the endometrial receptivity and improve therapeutic strategies to raise the pregnancy rate of ART.
