"5G + Blockchain"--enabled preimplantation genetic testing for precise prevention and control of rare disease
10.3760/cma.j.cn101441-20210113-00021
- VernacularTitle:“5G+区块链”赋能植入前遗传学检测技术用于罕见病的精准防控
- Author:
Lijun CAI
1
;
Songchang CHEN
;
Chenming XU
;
Hefeng HUANG
;
Li JIN
Author Information
1. 上海交通大学医学院 200025
- Publication Type:Journal Article
- Keywords:
5th generation mobile networks;
Blockchain;
Preimplantation genetic testing;
Prevention and control;
Heredity;
Rare disease;
Next generation sequencing
- From:
Chinese Journal of Reproduction and Contraception
2021;41(6):486-495
- CountryChina
- Language:Chinese
-
Abstract:
Based on next generation sequencing, preimplantation genetic testing (PGT), with novel strategy of mutated allele revealed by sequencing with aneuploidy and linkage analyses (MARSALA) is an economic and effective primary measure to control rare diseases by helping patients to select embryo free of monogenic diseases and aneuploidy (chromosome abnormality). With the commercialization of 5th generation mobile networks (5G) technology, "5G+blockchain" has brought a new development trend to PGT in the field of accurately control rare diseases. Therefore, in the present study, we summarize the current status of PGT and the characteristics of 5G and blockchain, then propose a plan to build a genetic diagnosis cloud service platform, a collaborative diagnosis and treatment platform for rare diseases, and a gene mutation database of Chinese population genetic disease, based on technology of 5G and blockchain in order to grasp the bonus of 5G era and promote the development of prevention and control of rare disease.
