Effects of the interval between laparoscopic proximal hydrosalpinx ligation combined with salpingostomy operation and IVF-ET on pregnancy and neonate outcomes
10.3760/cma.j.cn101441-20200409-00204
- VernacularTitle:腹腔镜下输卵管近端结扎联合远端造口术与IVF-ET间隔时间对妊娠结局和子代出生情况影响的研究
- Author:
Lijuan FAN
1
;
Xiaojuan LI
1
;
Juanzi SHI
1
;
Haixia DUAN
1
Author Information
1. 西北妇女儿童医院，西安 710000
- Publication Type:Journal Article
- Keywords:
Fallopian tube diseases;
Salpingostomy;
Fertilization in vitro;
Embryo transfer;
Pregnancy outcome
- From:
Chinese Journal of Reproduction and Contraception
2021;41(5):425-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of the interval between laparoscopic proximal hydrosalpinx ligation combined with salpingostomy operation and in vitro fertilization-embryo transfer (IVF-ET) on pregnancy and neonate outcomes. Methods:The data of 274 of infertile patients who underwent IVF-ET after laparoscopic proximal hydrosalpinx ligation combined with salpingostomy operation from January 2017 to September 2018 were analyzed by a cohort respective study. All patients were divided into three groups according to the interval between operation and embryo transfer, group A: one month interval ( n=114); group B: two months interval ( n=92); group C: the interval was three months or above ( n=68). Main outcomes were clinical pregnancy rate and live birth rate; secondary outcomes included human chorionic gonadotropin (hCG) positive rate, implantation rate, ectopic pregnancy rate, abortion rate and neonate outcomes (birth weight, gestational age of delivery and birth defect rate). Cleavage embryo transfer outcomes and blastocyst transfer outcomes were analyzed retrospectively. Results:There were no significant differences among the three groups in clinical pregnancy rate and live birth rate after cleavage embryo transfer or blastocyst transfer. In addition, there were no significant differences among the three groups in hCG positive rate, implantation rate, ectopic pregnancy rate and abortion rate. In cleavage embryo transfer cycles, twin birth weight of group B was heavier than that of group C [(3.61±0.31) kg vs. (3.25±0.60) kg, P=0.014]. In blastocyst transfer cycles, twin gestational age of delivery in group C was elder than that of group B [(36.22±1.44) weeks vs. (34.14±3.11) weeks, P=0.012]. Conclusion:The interval between laparoscopic proximal hydrosalpinx ligation combined with salpingostomy operation and IVF-ET does not affect pregnancy outcome, but it may affect neonate outcome to some extent.
