Influencing factors for high risk foot in patients with type 2 diabetes mellitus of different ages and their relationship with controlling nutritional status score
10.3969/j.issn.1006-6187.2025.08.005
- VernacularTitle:不同年龄2型糖尿病患者高危足影响因素及与控制营养状态评分相关性的研究
- Author:
Xiangying ZHU
1
;
Xiaozhen JI
1
Author Information
1. 323000 丽水市人民医院内分泌科
- Publication Type:Journal Article
- Keywords:
Controlling nutritional status score;
Diabetes mellitus,type 2;
Diabetic foot;
High risk
- From:
Chinese Journal of Diabetes
2025;33(8):582-586
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the influencing factors for high risk foot(HDF)and the controlling nutritional status(CONUT)score in patients with type 2 diabetes mellitus(T2DM)at different ages.Methods A total of 1314 patients with T2DM hospitalized in the Department of Endocrinology of our hospital from January 2022 to January 2024 were enrolled.According to age and the international working group on diabetic foot risk classification system,they were divided into the elderly low-risk(ELR)group with age≥65 years old and grade 0(n=294),the elderly high-risk(EHR)group with aged≥65 years and grade 1～3(n=138);non-elderly low-risk(NELR)group with age<65 years and grade 0(n=636),and non-elderly high-risk group(NEHR)with the age<65 years and grade 1～3(n=246).The general data,biochemical indexes and CONUT scores of patients with different ages and different risk levels were compared among the groups.Spearman correlation analysis was used to analyze the correlation between HDF grade and CONUT score in different age groups,and Logistic regression analysis was used to analyze the influencing factors for high-risk foot in T2DM patients of different ages.Results The age,DM duration,smoking,hemoglobin A1c(HbA1c),and CONUT score were higher in the EHR group than in the ELR group(P<0.05),while the hemoglobin and albumin(ALB)were lower in the EHR group than in the ELR group(P<0.05).The DM duration,smoking,FPG and HbA1c were higher in the NEHR group than in the NELR group(P<0.05),while ALB was lower than that in the NELR group(P<0.05).Spearman correlation analysis showed that the risk level of HDF in patients aged≥65 years was positively correlated with the CONUT score(r=0.301,P<0.001),while in patients aged<65 years,the risk level of HDF was not correlated with the CONUT score(r=0.055,P=0.102).Logistic regression analysis showed that age(OR 1.714,95%CI 1.420～2.067),DM duration(OR 1.062,95%CI 1.001～1.126),smoking(OR 3.986,95%CI 1.469～10.814),HbA1c(OR 1.246,95%CI 1.008～1.541),and CONUT score(OR 1.550,95%CI 1.051～2.286)were the influencing factors for the occurrence of HDF in T2DM patients aged≥65 years.DM duration(OR 1.051,95%CI 1.023～1.080),HbA1c(OR 1.141,95%CI 1.052～1.238)and FPG(OR 1.071,95%CI 1.019～1.125)were influencing factors for the occurrence of HDF in T2DM patients aged<65 years.Conclusions DM duration,HbA1c,etc.are the influencing factors for HDF in patients with T2DM,while the CONUT score is the influencing factor for the occurrence of HDF only in T2DM patients aged≥65 years.
