Research progress on pro-angiogenesis after frozen-thawed ovarian tissue transplantation
10.3760/cma.j.cn101441-20200402-00181
- VernacularTitle:冻融卵巢组织移植后促血管生成研究进展
- Author:
Libing HE
1
;
Xuemei FAN
;
Qin ZENG
;
Weixin LIU
Author Information
1. 成都医学院附属妇女儿童医院/四川省妇幼保健院生殖医学重点实验室 610045
- Publication Type:Journal Article
- Keywords:
Ovary;
Cryopreservation;
Transplantation;
Angiogenesis
- From:
Chinese Journal of Reproduction and Contraception
2021;41(1):79-84
- CountryChina
- Language:Chinese
-
Abstract:
Ovarian tissue cryopreservation and transplantation technology plays an important role in preserving female fertility. However, the ischemic injury after frozen-thawed ovarian tissue transplantation is a key issue for the survival of the transplanted ovarian tissue and the restoration of reproductive endocrine function. The use of appropriate ovarian tissue cryopreservation and transplantation techniques, or the addition of angiogenic factors, hormones, antioxidants, and Chinese medicine can effectively promote the angiogenesis of frozen-thawed ovarian tissue after transplantation, and improve the survival rate of follicles and the recovery of reproductive function. This article reviews the occurrence of ischemic injury after frozen-thawed ovarian tissue transplantation and how to promote angiogenesis.
