Establishment and Application of Drug Utilization Evaluation Criteria for Belimumab
10.3870/j.issn.1004-0781.2025.07.017
- VernacularTitle:贝利尤单抗药物利用评价标准的建立与应用
- Author:
Niya HUANG
1
;
Ling MA
;
Juan LIANG
;
Zhiqing ZHANG
Author Information
1. 云南省第一人民医院/昆明理工大学附属医院药学部,昆明 650032
- Publication Type:Journal Article
- Keywords:
Belimumab;
Drug utilization evaluation criteria;
Rational drug use;
Systemic lupus erythematosus
- From:
Herald of Medicine
2025;44(7):1111-1116
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop and validate an evaluation criteria for the clinical utilization of belimumab and to provide a reference for the rationally clinical use of belimumab.Methods Based on the drug instructions of belimumab,reference for rational clinical guidelines,and expert consensus,the drug utilization evaluation criteria for belimumab were established.A retrospective analysis was conducted to assess the rational use of belimumab in inpatients at a hospital in Yunnan Province from January 2021 to June 2024.Results A total of 1 809 medical records were included,involving 213 patients.The rationality rate of belimumab use was 72.5％,with 1 311 cases fully meeting the evaluation criteria.Non-compliance was primarily attributed to medication frequency(15.0％),dosage(9.8％),medication monitoring(4.3％),and efficacy evaluation(3.3％).Conclusions There is a need to enhance the management of dosage,medication monitoring,and efficacy evaluation to further standardize the rational use of belimumab in clinical practice.The drug utilization evaluation criteria established for belimumab are feasible and provide a reference for guiding its rational clinical application.
