Advances in research on endometrial receptive array and accurate judgment of window of implantation
10.3760/cma.j.cn101441-20190905-00405
- VernacularTitle:子宫内膜容受性阵列对子宫内膜种植窗精准判断的研究进展
- Author:
Shiyuan WEI
1
;
Jiaojiao XU
;
Tianyang GAO
;
Zhenbo OUYANG
Author Information
1. 广东省第二人民医院生殖医学中心，广州 510317
- Publication Type:Journal Article
- Keywords:
Endometrial receptivity array;
Window of implantation;
Receptivity of endometrial;
Personalized embryo transfer
- From:
Chinese Journal of Reproduction and Contraception
2020;40(10):814-818
- CountryChina
- Language:Chinese
-
Abstract:
Although assisted reproductive technology has made great progress, the recurrent implantation failure of embryos remains a dilemma to be solved. The key to improve the implantation rate lies in the developmental synchronization of endometrium with embryo and the maximum receptivity to embryos. Due to individualized differences in window of implantation (WOI) time, it is difficult in the field of assisted reproduction to accurately judge the optimal time for embryo implantation. Previous researches mostly used transvaginal ultrasound, serum estrogen and progesterone levels, endometrial biopsy and other methods to judge the time of endometrial WOI. However, errors remain. Recent years, big achievement has been made in modern molecular genetic diagnosis and microarray technology. Some scholars have also applied it to judge the endometrial receptivity and WOI, and found that it has a good guiding value. This article reviews the basic situation, clinical application and application prospect of endometrial receptivity array in order to provide reference for personalized embryo transfer (pET) in infertility patients.
