Visual field loss caused by torasemide
10.3760/cma.j.cn114015-20211222-01293
- VernacularTitle:托拉塞米致视野缺失
- Author:
Jie HAO
1
;
Xiaotong YUAN
;
Yuwang LI
;
Fangchen PENG
;
Yuanping LI
Author Information
1. 山西省人民医院药学部，太原 030012
- Publication Type:Journal Article
- Keywords:
Sulfonylurea compounds;
Visual fields;
Drug-related side and adverse reactions;
Torasemide
- From:
Adverse Drug Reactions Journal
2022;24(6):329-331
- CountryChina
- Language:Chinese
-
Abstract:
A 53-year-old male patient with stage Ⅳ diabetic nephropathy received an IV infusion of torasemide 40 mg which was put into a small pot once daily for edema of both lower limbs. On the 3rd day of medication, the dose of torasemide was increased to 80 mg/d according to the doctor′s advice due to poor diuretic effect. Eight hours later, the patient developed bilateral visual occlusion and blurred vision. Ophthalmological examination showed normal visual acuity and intraocular pressure in both eyes. The loss of binocular visual field caused by torasemide was considered. Then the drug was discontinued. After 2 days of drug withdrawal, the patient′s visual field loss disappeared. Because of the patient′s disease condition, IV infusion of torasemide 40 mg which was put into a small pot once daily was given again for 6 days, and the patient did not develop symptoms of visual field loss. The change of visual field might be related to the high dose of torasemide.
