MDT treatment strategy for organophosphorus and anticoagulant rodenticide poisoning in an elderly patient with depression
- VernacularTitle:1例老年抑郁患者有机磷和抗凝血鼠药中毒的MDT救治策略
- Author:
Shasha FU
1
;
Yue JIA
;
Hongxia SHAO
;
Yu GUO
;
Longyan MA
;
Tong HAN
;
Hao SUN
;
Hongzhi YU
Author Information
- Publication Type:Journal Article
- Keywords: organophosphate poisoning; blood coagulation disorders; consciousness disorders; coinfection; rodenticide poisoning; atropinization; multidisciplinary diagnosis and treatment
- From: Tianjin Medical Journal 2025;53(9):1000-1004
- CountryChina
- Language:Chinese
- Abstract: Organophosphorus pesticide(OP)is one of the most widely used pesticides in the world with the largest dosage.Acute organophosphorus pesticide poisoning(AOPP)is a common clinical disease,and AOPP accounts for 20%-50%of poisoning cases in China every year,with case fatality rate of 3%-40%.Bromophos(BDF)is a long-acting anticoagulant rodenticide,which inhibits vitamin K epoxide reductase and interferes with the synthesis of coagulation factorsⅡ,Ⅶ,Ⅸ and Ⅹ,leading to coagulation dysfunction.This article discusses the multidisciplinary diagnosis and treatment(MDT)process of a patient with combined poisoning of dichlorvos and bromadiolone.The article explores blood purification,management of coagulation abnormalities,secondary infection,atropinization and altered consciousnes in patients with organophosphorus poisoning and anticoagulant rodenticide compound poisoning,with the aim of providing clinicians with references for early diagnosis and treatment.
