Research progress of regulatory T cells in female reproductive process
10.3760/cma.j.cn101441-20190404-00137
- VernacularTitle:调节性T细胞在女性生殖过程中的研究进展
- Author:
Yunian ZHANG
1
;
Haiqing TIAN
1
;
Xiaolin LA
1
Author Information
1. 新疆医科大学第一附属医院生殖医学中心，乌鲁木齐 830054
- Publication Type:Journal Article
- Keywords:
Regulatory T cell;
Infertility;
Follicular development;
Immunological tolerance
- From:
Chinese Journal of Reproduction and Contraception
2020;40(3):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Regulatory T (Treg) cells are a subtype of lymphocytes with immune suppressive function, and are abundantly expressed on ovarian and endometrium. They have the functions of regulating follicular development, suppressing immune response, promoting maternal-fetal immune tolerance and maintaining early pregnancy during reproduction. The abnormal expressing of Tregs is closely related to the occurrence and development of female reproductive diseases, and it is expected to become a new diagnostic marker and therapeutic target in reproductive medicine.
