Evaluation of complexity metrics in helical tomotherapy and their correlations with dosimetric verification
10.3969/j.issn.1005-202X.2025.08.002
- VernacularTitle:螺旋断层放疗计划复杂性评价与剂量验证相关性
- Author:
Feng LIN
1
;
Jinyan HU
1
;
Mingchao HUANG
1
;
Xiaping WEI
1
Author Information
1. 广州中医药大学金沙洲医院肿瘤放射治疗中心,广东 广州 510168
- Publication Type:Journal Article
- Keywords:
helical tomotherapy;
complexity metric;
dosimetric verification;
correlation analysis
- From:
Chinese Journal of Medical Physics
2025;42(8):990-996
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the complexity of helical tomotherapy plans for different anatomical sites and explore its correlations with dosimetric verification.Methods A total of 71 complexity metrics of the helical tomotherapy plans executed by Accuray?planning system v.5.1.9.2 for nasopharyngeal carcinoma(n=52),breast cancer(n=19),cervical cancer(n=52)and central nervous system cancer(n=37)were analyzed.The correlations between metrics were analyzed,and principal component analysis was used for dimensionality reduction.The global complexity score(normalized plan complexity score,nPCS)was calculated.The top-contributing complexity metrics within the first 10 principal components were extracted,and a correlation analysis with the gamma passing rate was conducted.Results There was no significant correlation between most metrics.The global complexity score was different for different sites,with the highest median nPCS and the most complex plan in the head and neck cancer.The correlation analysis between the global complexity score and gamma passing rate revealed that in the central nervous system plans,CFNS90 and EPSTV1_0 had strong correlations with gamma passing rate for 3%/2 mm criterion,and a significant correlation was found between CFNS90 and gamma passing rate for 3%/3 mm criterion.Conclusion Complexity scores can quantize the complexity of helical tomotherapy plans for different sites,and certain metrics are correlated with gamma passing rate.
