Discussion on the Treatment of Lung Cancer by"Regulating Spirit and Invigorating Qi"Based on the View of"Chronic Stress-Tumor Immune Microenvironment"
10.11842/wst.20241127001
- VernacularTitle:"慢性应激-TIME"视角下论肺癌"调神助气"诊疗策略的构建
- Author:
Jinyu WEN
1
;
Jiawei HE
;
Chuan ZHENG
;
Yang ZHONG
;
Yuling JIANG
;
Xi FU
;
Fengming YOU
;
Qiong MA
Author Information
1. 成都中医药大学附属医院 成都 610075
- Publication Type:Journal Article
- Keywords:
Lung cancer;
Tumor immune microenvironment;
Regulating spirit and invigorating qi;
Chronic stress
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2025;27(8):2244-2253
- CountryChina
- Language:Chinese
-
Abstract:
Chronic stress triggers the imbalance of the homeostasis of the tumor immune microenvironment(TIME),which is a key factor driving the development of lung cancer.Based on the mapping relationship between the concept of"spirit"in traditional Chinese medicine and chronic stress,and between"qi"and"immunity",it is believed that the cross-linking mechanism of"chronic stress-TIME-lung cancer"aligns with the understanding of traditional Chinese medicine of disease as involving the interplay between the"body,qi and spirit".The disorganization of"spirit"and"qi"is not only the root of the change of the"form",but also the key to prevent and control it.The treatment principle of synergizing to improve the chronic stress of"regulating the spirit"and remodeling the TIME of"invigorating the qi"is further proposed,which emphasizes on grasping the core pathogenesis of lung cancer at each stage of its evolution in order to administer medicines,drawing on the clinical experience and pharmacological research results in order to accurately hit the target,and combining special therapies like acupuncture,Chinese kungfu,sound therapy to treat the change of"shape"by modulating neuro-endocrine-immune network homeostasis,so as to provide new ideas and accessible solutions for the comprehensive prevention and treatment system of lung cancer.
