Effect of TCM combined with acupuncture on heart function in patients with chronic heart failure:a systematic review and meta-analysis
10.3969/j.issn.1008-0074.2025.04.09
- VernacularTitle:中药联合针刺对慢性心力衰竭患者心功能康复效果的系统评价
- Author:
Bing WU
1
;
Li-wei WANG
;
Tao WANG
Author Information
1. 西安市高新医院中医科,陕西西安 710000
- Publication Type:Journal Article
- Keywords:
Heart failure;
Acupuncture;
Evidence-based medicine
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2025;34(4):481-486
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This systematic review and meta-analysis aims to evaluate the effect of traditional Chinese medicine(TCM)combined with acupuncture on chronic heart failure(CHF).Methods:CNKI,CBM,VIP,Wanfang database,the Cochrane Library,PubMed and Embase databases were searched for randomized controlled trials that com-pare the clinical efficacy between TCM combined acupuncture therapy and routine western medical treatment on CHF from establishment to July 23rd,2024.Results:A total of 14 studies were included in the final analysis.Compared to patients in control group,those in trial group had significant higher total effective rate[OR=3.84,95%CI(2.58,5.72),P<0.001]and left ventricular ejection fraction[MD=4.69,95%CI(3.74,5.63),P<0.001],and significant lower left ventricular end-systolic diameter[MD=-3.35,95%CI(-5.24,-1.46),P<0.001],left ventricular end-diastolic diameter[MD=-3.54,95%CI(-5.08,-2.00),P<0.001],levels of N terminal pro brain natriuretic peptide[SMD=-1.72,95%CI(-2.28,-1.15),P<0.001],high sensitive C reactive protein[MD=-6.73,95%CI(-10.16,-3.31),P<0.001],tumor necrosis factor-α[SMD=-3.77,95%CI(-6.08,-1.45),P=0.001]and interleukin-6[SMD=-1.52,95%CI(-2.21,-0.82),P<0.001].Conclusion:Traditional Chinese medicine combined with acupuncture may improve the cardiac structure and function,reduce the level of NT-proBNP,and has a certain effect of inhibiting micro-inflammation in patients with chronic heart failure.