Advances in pharmacological effects of demethyleneberberine
10.12360/CPB202402004
- VernacularTitle:去亚甲基小檗碱的药理作用研究进展
- Author:
Jing-qi LI
1
;
Qi ZHANG
1
;
Yu-tong CHEN
1
;
Yong-bin TONG
1
;
Cheng-yu LU
1
Author Information
1. 广东医科大学药学院,广东东莞 523808
- Publication Type:Journal Article
- Keywords:
demethyleneberberine;
pharmacological effects;
anti-infection;
anti-inflammation;
hepatoprotection;
neuropro-tection
- From:
Chinese Pharmacological Bulletin
2025;41(1):7-12
- CountryChina
- Language:Chinese
-
Abstract:
Demethyleneberberine(DMB),one of the active me-tabolite of berberine,displays versatile pharmacological proper-ties.Numerous studies indicate diverse biological activities,such as actions against infection,inflammation,fibrosis,cancer cells,blood lipids,etc.It presents considerable potential in treating neurodegenerative diseases.This article provides a con-cise review of the pharmacological actions and mechanisms made in demethyleneberberine research to facilitate a deeper under-standing of its pharmacology and provide a scientific foundation for its prudent development.
