Pharmaceutical Care for An Elderly Patient with mGluR5 Antibody Encephalitis Treated with Ofatumumab
10.3870/j.issn.1004-0781.2025.01.015
- VernacularTitle:奥法妥木单抗治疗高龄难治性抗代谢型谷氨酸受体5脑炎的药学监护
- Author:
Lingna GAO
1
;
Xiaoli ZHU
;
Xueting DU
;
Jingzhe HAN
Author Information
1. 衡水市人民医院药学部,衡水 053000
- Publication Type:Journal Article
- Keywords:
Ofatumumab;
mGluR5 antibody encephalitis;
Advanced age;
Pharmaceutical care
- From:
Herald of Medicine
2025;44(1):116-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the involvement of pharmacists in the pharmaceutical care of olfacatumumab in the treatment of elderly patients with refractory anti-metabotropic glutamate receptor 5(mGluR5)encephalitis and to provide a reference for the treatment and pharmaceutical care of patients with refractory autoimmune encephalitis(AE).Methods An 81-year-old patient with anti-mGluR5 encephalitis who had poor first-line immunotherapy effect.The key points of pharmaceutical care were determined according to the patient's condition and the characteristics of therapeutic drugs.The drug selection,administration mode,drug interaction,adverse reactions,and precautions of ofatumumab were put forward.At the same time,the patients and their families were given medication guidance and discharge education,and regular follow-up was carried out.Results With the cooperation of doctors,the patient was provided with whole-process pharmaceutical care,and the patient's condition was improved,and the patient's condition was good so far.Conclusion Clinical pharmacists pay attention to the effectiveness and safety of the treatment with ofatumumab by carrying out individualized pharmaceutical care for this patient,which fully reflects the value of clinical pharmacists and provides a reference for the treatment and pharmaceutical care of refractory AE patients.
