A review on cell-based models of human pancreatic diseases in vitro
10.12360/CPB202307032
- VernacularTitle:胰腺疾病体外细胞模型研究进展
- Author:
Wei-feng ZHU
1
;
Li-jun PENG
;
Jing LIU
;
Shu-hong PENG
Author Information
1. 江西中医药大学现代中药制剂教育部重点实验室
- Publication Type:Journal Article
- Keywords:
pancreatic diseases;
cell model;
cell characteris-tics;
culture method;
modeling method;
evaluation index
- From:
Chinese Pharmacological Bulletin
2025;41(1):23-29
- CountryChina
- Language:Chinese
-
Abstract:
Unhealthy diet,smoking and drinking can cause a variety of pancreatic diseases,including pancreatitis,diabetes and pancreatic cancer,which seriously threaten human health.The construction of cell models in vitro is of great significance in the study of the etiology and pathogenesis of pancreatic diseases and the development and screening of medicines.At present,domestic and foreign scholars have developed a variety of in vitro pancreatic disease models.In this paper,we summarize the cell models of common pancreatic diseases in vitro,and review the characteristics,culture methods,modeling methods,and evalu-ation indexes of the model cells,so as to provide references for researchers related to pancreatic diseases.
