A Comparative Study of Outcomes Used in Trials for postoperative bowel dysfunction in rectal cancer Treated by Western Medicine and Traditional Chinese Medicine
- VernacularTitle:中西医治疗直肠癌术后排便功能障碍的结局指标比较研究
- Author:
Meiji LU
1
;
Rui ZHANG
;
Rui LI
;
Rongyan PENG
;
Yufei YANG
Author Information
- Publication Type:Journal Article
- Keywords: Rectal cancer; Bowel dysfunction; Low anterior resection syndrome; LARS; Clinical evaluation indicator; Outcome indicator
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(10):2739-2747
- CountryChina
- Language:Chinese
- Abstract: Objective The purpose of this study is to compare and analyze the outcome indicators for the combined Chinese and Western medicine treatment of postoperative bowel dysfunction in rectal cancer,divide the indicator domains.Methods Eight major Chinese and English databases and two clinical registration centers were searched for RCTs.The outcome indicators reported were extracted and analyzed.Results A total of 121 Western medicine RCTs,25 Chinese and Western medicine combined RCTs,and 8 Chinese medicine RCTs were obtained,93 outcome indicators were obtained and divided into five core domains and 13 outcome domains.Western medicine RCTs outcome indicators are often used in the Low Anterior Resection Syndrome Score(LRASS),anal rectal pressure,and the Quality of Life Questionnaire-Core 30(QLQ-30).Chinese medicine RCTs outcome indicators are often used in the Chinese clinical efficacy judgment standard,Chinese symptom evaluation,and the LARSS.Chinese and Western medicine combined RCTs outcome indicatorsare are often used in the Xu Zhongfa Five-Point Scale,LARSS,and anal rectal pressure.Conclusion The RCTs on Chinese and Western medicine treatment of postoperative bowel dysfunction in rectal cancer currently have issues such as overall low quality,less use of compliance and economic indicators,and lack of traditional Chinese medicine characteristics.Based on these problems,this study proposes to construct the core index set of defecation dysfunction after rectal cancer with TCM characteristics.
