Mediating effect of family resilience on the relationship between psychological resilience and demoralization in leukemia patients undergoing chemotherapy
10.3760/cma.j.cn115682-20250309-01142
- VernacularTitle:家庭抗逆力在白血病化疗患者心理弹性和失志水平间的中介效应分析
- Author:
Juan GUO
1
;
Na LIU
1
;
Yihong DING
1
Author Information
1. 郑州大学第一附属医院血液内科，郑州 450000
- Publication Type:Journal Article
- Keywords:
Leukemia;
Chemotherapy;
Family resilience;
Psychological resilience;
Demoralization syndrome;
Mediating effect
- From:
Chinese Journal of Modern Nursing
2025;31(29):4014-4019
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the mediating effect of family resilience on the relationship between psychological resilience and demoralization in leukemia patients undergoing chemotherapy.Methods:A total of 240 leukemia patients hospitalized for chemotherapy in the Department of Hematology, the First Affiliated Hospital of Zhengzhou University, from January to December 2024 were selected by convenience sampling. The Basic Information Questionnaire, Family Hardiness Index (FHI), Connor-Davidson Resilience Scale (CD-RISC), and the Chinese version of the Demoralization Scale Ⅱ (DS-Ⅱ) were administered. Pearson correlation analysis was used to examine the associations among family resilience, psychological resilience, and demoralization. A structural equation model was constructed with AMOS 21.0 to verify the mediating effect. A total of 240 questionnaires were distributed, of which 232 were valid, yielding a valid response rate of 96.67% (232/240) .Results:The mean scores of the 232 patients were as follows: FHI (51.41±8.27), CD-RISC (51.84±7.96), and DS-Ⅱ (21.03±4.19). FHI was positively correlated with CD-RISC ( P<0.05), while DS-Ⅱ was negatively correlated with both FHI and CD-RISC ( P<0.05). Psychological resilience had a direct negative effect on demoralization ( P<0.01), and family resilience also had a direct negative effect on demoralization ( P<0.01). Family resilience partially mediated the relationship between psychological resilience and demoralization ( P<0.01), accounting for 59.96% (-0.289/-0.482) of the total effect. Conclusions:Psychological resilience and family resilience in leukemia patients undergoing chemotherapy were both at moderate levels, while demoralization was relatively high. Family resilience partially mediated the relationship between psychological resilience and demoralization.
